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Clinical Protocol to Investigate the Efficacy of Amlexanox for Treatment of Glucose and Lipid Abnormalities in Obese Type 2 Diabetes
This study is researching all of the following topics: Overweight ( Obesity ) Type 2 diabetes ( Type 2 diabetes mellitus )
Location of study visits: Ann Arbor, MI
This study is looking for: male   female  Both men and women
  • Volunteers with specific conditions
  • 18 years to 999 years
The reason for this study is to find out how an investigational medicine, Amlexanox, can improve type 2 diabetes, insulin resistance, obesity and non-alcoholic fatty liver disease (NAFLD).
268 HEROES have already shown interest in this study. I am interested! Print Study | Contact Study Team
Who can participate?
What is involved? This study involves the use of a research drug, Amlexanox, for the treatment of type 2 diabetes, insulin resistance, obesity and non-alcoholic fatty liver disease (NAFLD). Amlexanox is taken orally in a pill three times a day. We plan to continue therapy for a period of 12 weeks followed by a follow-up 4 weeks after therapy ends. We will evaluate the changes in metabolic parameters (e.g. blood cholesterol, liver function, insulin resistance) and body composition characteristics (e.g. the pattern of fat distribution in the body). Seven eligible subjects in this study will also be evaluated for a change in liver disease by a liver biopsy.
Compensation $600-$9,999
More about the study

IRB number: HUM00065177
Study posted on: 04/29/2013
Posting will be taken down on: 04/29/2015
Study Team Principal Investigator:  Oral, Elif A Department:  Internal Medicine - Metabolism, Endocrinology & Diabetes
For questions about this study, contact: Adam Neidert
(734) 615-0539
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